Endocrine Abstracts

There is evidence that the 'large offspring syndrome' of in-vitro produced ruminant fetuses results from altered expression of imprinted genes which regulate fetal growth. DNA was isolated from tissue samples which were obtained at a public slaughterhouse, and a new length polymorphism was identified in the 3`UTR of the bovine IGF2-gene. This polymorphism was used to identify heterozygous animals and to characterize IGF2-imprinting in normal fetal and adult bovine tissues. Tot...